Hyperbaric system for oxygen toxicity studies in the toad urinary bladder

Authors:
  • JMJ. H. Miller
    J. H. Miller
  • DHD. Hall
    D. Hall
  • DHD. Haworth
    D. Haworth
  • SMS. A. Mendoza
    S. A. Mendoza
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Abstract
A hyperbaric research system to study the effects on membrane function of oxygen at pressures as high as 20 ATA has been designed. The system includes a pressure chamber capable of holding eight isolated toad bladder short-circuit current apparatuses and unique experimental gassing, diluent addition, and sampling systems which are monitored by a control panel mounted on the side of the pressure chamber. These externally controlled gassing, diluent, and sampling systems permit experimental manipulations at any ambient pressure and are a significant addition to the methodology of hyperbaric research.