The Effect of Changes in Arterial Blood Pressure on the Rate of Aqueous Humour Formation in a Primate (Cercopithecus ethiops)

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  • ABA. Bill
    A. Bill
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Abstract
The rate of aqueous humour formation in vervet monkeys was determined with a dilution method during stepwise reductions in mean arterial blood pressure produced by bleeding the animals. The mean rate of aqueous humour formation at a mean arterial blood pressure of 119 ± 7 mm Hg was 2.64 ± 0.22 μl/min (n = 11). Bleeding the animals to a pressure of 70–90 mm Hg had little effect on the rate of aqueous formation. Further reductions in mean arterial blood pressure usually decreased aqueous formation markedly. Interruption of the sympathetic supply to the eye under study had no appreciable effect on the relationship between rate of aqueous humour formation and mean arterial blood pressure.