Use of directed evolution of mammalian cytochromes P450 for investigating the molecular basis of enzyme function and generating novel biocatalysts
Authors:
- Santosh KumarSKSantosh Kumar
- James R. HalpertJHJames R. Halpert
- 1 December 2005
- journal article
- review article
- Published by Elsevier in Biochemical and Biophysical Research Communications
- Vol. 338 (1) , 456-464
Abstract
No abstract availableKeywords
This publication has 64 references indexed in Scilit:
- Directed evolution of biocatalytic processesBiomolecular Engineering, 2005
- Exploring the potential of xenobiotic‐metabolising enzymes as biocatalysts: Evolving designer catalysts from polyfunctional cytochrome P450 enzymesClinical and Experimental Pharmacology and Physiology, 2005
- Role of Cytochrome P450 Phenotyping in Cancer TreatmentJournal of Clinical Oncology, 2005
- Directed evolution of enzymes for applied biocatalysisTrends in Biotechnology, 2003
- Regio- and Enantioselective Alkane Hydroxylation with Engineered Cytochromes P450 BM-3Journal of the American Chemical Society, 2003
- A Self‐Sufficient Peroxide‐Driven Hydroxylation BiocatalystAngewandte Chemie International Edition, 2003
- Dispelling the Myths--Biocatalysis in Industrial SynthesisScience, 2003
- Laboratory evolution of a soluble, self-sufficient, highly active alkane hydroxylaseNature Biotechnology, 2002
- Origins, Current Status, and Future Challenges of Green ChemistryAccounts of Chemical Research, 2002
- How enzymes adapt: lessons from directed evolutionTrends in Biochemical Sciences, 2001