miRNA-122 Protects Mice and Human Hepatocytes from Acetaminophen Toxicity by Regulating Cytochrome P450 Family 1 Subfamily A Member 2 and Family 2 Subfamily E Member 1 Expression
- 1 December 2017
- journal article
- Published by Elsevier in The American Journal of Pathology
- Vol. 187 (12) , 2758-2774
Abstract
No abstract availableKeywords
This publication has 46 references indexed in Scilit:
- Hepatic cytochromes P450: structural degrons and barcodes, posttranslational modifications and cellular adapters in the ERAD-endgameDrug Metabolism Reviews, 2016
- Mechanistic biomarkers in acetaminophen-induced hepatotoxicity and acute liver failure: from preclinical models to patientsExpert Opinion on Drug Metabolism & Toxicology, 2014
- A reproducible, clinically relevant, intensively managed, pig model of acute liver failure for testing of therapies aimed to prolong survivalLiver International, 2012
- Essential metabolic, anti-inflammatory, and anti-tumorigenic functions of miR-122 in liverJournal of Clinical Investigation, 2012
- Structure, function, regulation and polymorphism and the clinical significance of human cytochrome P450 1A2Drug Metabolism Reviews, 2009
- Mechanisms of Acetaminophen-Induced Liver Necrosis2009
- Mechanisms of Drug-Induced Liver DiseaseClinics in Liver Disease, 2007
- RETRACTED: Downregulation of miR‐122 in the rodent and human hepatocellular carcinomasJournal of Cellular Biochemistry, 2006
- Nuclear Translocation of Endonuclease G and Apoptosis-Inducing Factor during Acetaminophen-Induced Liver Cell InjuryToxicological Sciences, 2006
- Transcription coactivator peroxisome proliferator-activated receptor-binding protein/mediator 1 deficiency abrogates acetaminophen hepatotoxicityProceedings of the National Academy of Sciences, 2005