A Convenient Synthesis of 3-Cyano-2-methylpyridines under Ultrasonic Irradiation
Authors:
- 1 June 1988
- journal article
- Published by Oxford University Press (OUP) in Bulletin of the Chemical Society of Japan
- Vol. 61 (6) , 2199-2200
Abstract
Ultrasonic irradiation of α,β-unsaturated carbonyl compounds 1a–i with acetonitrile in the presence of potassium t-butoxide gave 3-cyano-2-methylpyridines 2a–i in moderate to good yields. The pyridines are produced by a Michael reaction of 3-iminobutanonitrile, an acetonitrile dimer, to the substrates 1a–i.Keywords
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