A comprehensive phenotypic CRISPR-Cas9 screen of the ubiquitin pathway uncovers roles of ubiquitin ligases in mitosis
- 1 March 2021
- journal article
- research article
- Published by Elsevier in Molecular Cell
- Vol. 81 (6) , 1319-1336.e9
Abstract
No abstract availableKeywords
Funding Information
- University of California, San Francisco
This publication has 114 references indexed in Scilit:
- TRIAD1 and HHARI bind to and are activated by distinct neddylated Cullin‐RING ligase complexesThe EMBO Journal, 2013
- A Ribosome-Bound Quality Control Complex Triggers Degradation of Nascent Peptides and Signals Translation StressCell, 2012
- Fiji: an open-source platform for biological-image analysisNature Methods, 2012
- Dynamics of Cullin-RING Ubiquitin Ligase Network Revealed by Systematic Quantitative ProteomicsCell, 2010
- HERC2 coordinates ubiquitin-dependent assembly of DNA repair factors on damaged chromosomesNature Cell Biology, 2009
- A promiscuous α-helical motif anchors viral hijackers and substrate receptors to the CUL4–DDB1 ubiquitin ligase machineryNature Structural & Molecular Biology, 2009
- E3 ligase activity of BRCA1 is not essential for mammalian cell viability or homology-directed repair of double-strand DNA breaksProceedings of the National Academy of Sciences, 2008
- FBW7 ubiquitin ligase: a tumour suppressor at the crossroads of cell division, growth and differentiationNature Reviews Cancer, 2008
- Structure of the Cul1–Rbx1–Skp1–F boxSkp2 SCF ubiquitin ligase complexNature, 2002
- Protein ubiquitination involving an E1–E2–E3 enzyme ubiquitin thioester cascadeNature, 1995