体外循环下心血管手术患者术后谵妄发生情况及影响因素分析
Open Access
- 1 July 2023
- journal article
- abstracts
- Vol. 54 (4) , 752-758
Abstract
探索体外循环下心血管手术患者的术后谵妄(postoperative delirium, POD)与亚谵妄综合征(subsyndromal delirium, SSD)发生情况及影响因素。 收集2022年5–9月湖北省某三甲医院体外循环下心血管手术患者的一般资料、围手术期血常规及生理生化指标、手术及治疗情况等,采用护理谵妄筛查量表评估结局指标即POD和SSD发生情况,不同组别的影响因素分析采用无序多分类logistic回归。 202例患者中,SSD、SSD进展为POD、直接发生POD的发生率为13.4%、6.4%、34.2%。回归分析显示,以无POD或SSD组为对照,术前血糖〔比值比(odds ratio, OR)=0.38,95%置信区间(CI):0.19~0.76)〕、术中输注血小板(OR=0.37,95%CI:0.15~0.92)、术中依托咪酯剂量(OR=0.93,95%CI:0.87~0.98)、术后总胆红素水平(OR=1.04,95%CI:1.01~1.07)是SSD的影响因素;年龄(OR=1.09,95%CI:1.01~1.17)、ASA分级为Ⅳ级及以上(OR=10.72,95%CI:1.85~62.08)、术中右美托咪定剂量(OR=1.01,95%CI:1.003~1.02)、机械通气时长(OR=1.04,95%CI:1.01~1.07)是SSD进展为POD的影响因素;年龄(OR=1.06,95%CI:1.02~1.10)、初中或高中学历(OR=0.35,95%CI:0.15~0.83)、机械通气时长(OR=1.04,95%CI:1.01~1.07)是直接发生POD的影响因素。 年龄、受教育程度、ASA分级、术前血糖、术中输注血小板、术中依托咪酯剂量、术中右美托咪定剂量、术后总胆红素和机械通气时长是体外循环下心血管手术患者POD和SSD发生情况的影响因素,且不同组别的影响因素存在差异,应精准评估和干预不同组别的危险因素,预防或遏制POD或SSD的发生和发展,促进患者加速康复。Keywords
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