Amino Alcohol Mediated Enantioselective Addition of 2-Phenylethynylzinc Bromide to Aldehydes

Authors:
  • GTG. M. Ramos Tombo
    G. M. Ramos Tombo
  • EDE. Didier
    E. Didier
  • BLB. Loubinoux
    B. Loubinoux
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Abstract
Optically active secondary phenylalkynyl alcohols were obtained in good yields and selectivities via (-)-N-methyl-ephedrine lithium salt mediated addition of 2-phenylethynylzinc bromide to alkyl and aryl aldehydes.