Exploring effects of type 2 diabetes on cognitive functioning in older adults.
Authors:
- 1 January 2009
- journal article
- Published by American Psychological Association (APA) in Neuropsychology
- Vol. 23 (1) , 1-9
Abstract
Type 2 diabetes may be associated with exacerbated aging-related declines in cognitive neuropsychological performance. The authors examined whether such effects are systematic (i.e., broadly distributed across domains or domain-specific) or moderated by age (i.e., varying across age within older adults). The authors assembled recent cross-sectional data from the Victoria Longitudinal Study (VLS) Sample 3 (Wave 1; initial n = 570; initial age = 53-90 years). Using a comprehensive, multidimensional spectrum of cognitive neuropsychological tests, the authors examined performance differences by diabetes status (diabetes group vs. healthy controls) and age (young-old vs. old-old). Our results showed that healthy controls significantly outperformed the diabetes group only on markers of executive functioning and speed. Notably, the diabetes-related effects were robust across the two late-life age groups. Future research examining longitudinal changes is recommended.Keywords
Funding Information
- National Institutes of Health (R37 AG008235)
- Canada Research Chairs Program
This publication has 45 references indexed in Scilit:
- Diabetes and Function in Different Cognitive Systems in Older Individuals Without DementiaDiabetes Care, 2006
- Impact of impaired glucose tolerance and type 2 diabetes on cognitive agingNeurobiology of Aging, 2005
- Episodic memory change in late adulthood: Generalizability across samples and performance indicesMemory & Cognition, 2004
- Diabetes Mellitus and Risk of Alzheimer Disease and Decline in Cognitive FunctionArchives of Neurology, 2004
- The Unity and Diversity of Executive Functions and Their Contributions to Complex “Frontal Lobe” Tasks: A Latent Variable AnalysisCognitive Psychology, 2000
- Diabetes prevalence and socioeconomic status: a population based study showing increased prevalence of type 2 diabetes mellitus in deprived areasJournal of Epidemiology and Community Health, 2000
- Hypertension and neuropsychological function: A lifespan perspectiveExperimental Aging Research, 1995
- Rey auditory-verbal learning test: Structure analysisJournal of Clinical Psychology, 1993
- Is questionnaire information valid in the study of a chronic disease such as diabetes? The Nord-Trøndelag diabetes study.Journal of Epidemiology and Community Health, 1992
- A longitudinal study of cognitive performance in noninsulin dependent (type II) diabetic menExperimental Gerontology, 1986