Fatty acid amide hydrolase inhibitors. Surprising selectivity of chiral azetidine ureas
- 1 August 2009
- journal article
- research article
- Published by Elsevier in Bioorganic & Medicinal Chemistry Letters
- Vol. 19 (15) , 4241-4244
Abstract
No abstract availableKeywords
This publication has 11 references indexed in Scilit:
- Selective blockade of 2-arachidonoylglycerol hydrolysis produces cannabinoid behavioral effectsNature Chemical Biology, 2008
- Selectivity of inhibitors of endocannabinoid biosynthesis evaluated by activity-based protein profilingBioorganic & Medicinal Chemistry Letters, 2008
- Structure-guided inhibitor design for human FAAH by interspecies active site conversionProceedings of the National Academy of Sciences, 2008
- Thiadiazolopiperazinyl ureas as inhibitors of fatty acid amide hydrolaseBioorganic & Medicinal Chemistry Letters, 2008
- Activity-Based Protein Profiling: From Enzyme Chemistry to Proteomic ChemistryAnnual Review of Biochemistry, 2008
- Enzymatic Pathways That Regulate Endocannabinoid Signaling in the Nervous SystemChemical Reviews, 2008
- Novel Mechanistic Class of Fatty Acid Amide Hydrolase Inhibitors with Remarkable SelectivityBiochemistry, 2007
- Fatty acid amide hydrolase inhibitors display broad selectivity and inhibit multiple carboxylesterases as off-targetsNeuropharmacology, 2007
- Discovery of a Potent, Selective, and Efficacious Class of Reversible α-Ketoheterocycle Inhibitors of Fatty Acid Amide Hydrolase Effective as AnalgesicsJournal of Medicinal Chemistry, 2004
- Mice lacking fatty acid amide hydrolase exhibit a cannabinoid receptor-mediated phenotypic hypoalgesiaPain, 2004