Construction of the highly oxidized bicyclo[3.2.1]octane CD ring system of aconitine via a late stage enyne cycloisomerization
- 6 October 2018
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Chemical Communications
- Vol. 54 (86) , 12258-12261
Abstract
An enyne cycloisomerization enables assembly of the highly oxidized bicyclo[3.2.1]octane CD rings of the complex diterpenoid alkaloid aconitine.Keywords
Funding Information
- National Natural Science Foundation of China (21572139)
- National Natural Science Foundation of China (21732005)
This publication has 35 references indexed in Scilit:
- Total Synthesis of (−)-N-Methylwelwitindolinone C IsothiocyanateJournal of the American Chemical Society, 2011
- Total Synthesis ofN-Methylwelwitindolinone D IsonitrileJournal of the American Chemical Society, 2011
- Differential Reactivities of Enyne Substrates in Ruthenium- and Palladium-Catalyzed CycloisomerizationsJournal of the American Chemical Society, 2010
- Diterpenoid alkaloidsNatural Product Reports, 2010
- C−H Amination in Synthesis: An Approach to the Assembly of the B/C/D Ring System of AconitineOrganic Letters, 2007
- Aconitine-Induced Increase and Decrease of Acetylcholine Release in the Mouse Phrenic Nerve-Hemidiaphragm Muscle PreparationThe Japanese Journal of Pharmacology, 1994
- Total synthesis of delphinine-type alkaloids by simple, fourth generation methodsPure and Applied Chemistry, 1979
- A new stereospecific total synthesis of chasmanine and 13-desoxydelphonineCanadian Journal of Chemistry, 1978
- Total synthesis of talatisamine, a delphinine type alkaloidJournal of the American Chemical Society, 1974
- Aconitum‐Alkaloide, XI. Mitteilung Die Struktur des AconitinsEuropean Journal of Organic Chemistry, 1959