Involucrin expression in adnexal skin tumours
Authors:
- 1 January 1986
- journal article
- research article
- Published by Springer Nature in Virchows Archiv
- Vol. 408 (5) , 527-540
Abstract
The expression of involucrin was studied in a group of skin neoplasms, mostly of adnexal origin. As happens with other types of epithelial tumours, involucrin was detected in the most differentiated areas (presenting a squamoid or ductal differentiation). No reactivity was observed in non-epithelial skin tumours. These results suggest that involucrin is a specific marker for epithelial and adnexal differentiation of skin tumours and may thus be a useful aid in histopathologic diagnosis and classification of neoplasms.Keywords
This publication has 11 references indexed in Scilit:
- Stewart‐Treves syndrome: an histogenetic (ultrastructural and immunohistological) studyJournal of Cutaneous Pathology, 1986
- Abnormal maturation pathway of keratinocytes in psoriatic skinBritish Journal of Dermatology, 1985
- Neuroendocrine (Merkel) cells of the skin: hyperplasias, dysplasias, and neoplasms.1985
- Involucrin, a marker of squamous and urothelial differentiation. An immunohistochemical study on its distribution in normal and neoplastic tissuesThe Journal of Pathology, 1985
- Identification of Merkel cells in human skin by specific cytokeratin antibodies:Differentiation, 1984
- Involucrin Expression in Normal and Neoplastic Human Skin: A Marker for Keratinocyte DifferentiationJournal of Investigative Dermatology, 1984
- Involucrin in Squamous and Basal cell Carcinomas of the Skin: An Immunohistochemical StudyJournal of Investigative Dermatology, 1984
- Postmastectomy angiosarcoma (Stewart-Treves syndrome)American Journal of Surgical Pathology, 1983
- Involucrin synthesis and tissue assembly by keratinocytes in natural and cultured human epithelia.Journal of Cell Biology, 1981
- Presence in human epidermal cells of a soluble protein precursor of the cross-linked envelope: Activation of the cross-linking by calcium ionsCell, 1979