Faecal Microbiota Transplantation, Paving the Way to Treat Non-Alcoholic Fatty Liver Disease
Authors:
- María Del BarrioMBMaría Del Barrio
- Lucía LavínLLLucía Lavín
- Álvaro Santos-LasoÁSÁlvaro Santos-Laso
- Maria Teresa Arias-LosteMAMaria Teresa Arias-Loste
- Aitor OdriozolaAOAitor Odriozola
- Juan Carlos Rodriguez-DuqueJRJuan Carlos Rodriguez-Duque
- Coral RivasCRCoral Rivas
- Paula IruzubietaPIPaula Iruzubieta
- Javier CrespoJCJavier Crespo
Open Access
- 24 March 2023
- journal article
- review article
- Published by MDPI AG in International Journal of Molecular Sciences
- Vol. 24 (7) , 6123
Abstract
Non-alcoholic fatty liver disease (NAFLD) is currently the most prevalent cause of chronic liver disease (CLD). Currently, the only therapeutic recommendation available is a lifestyle change. However, adherence to this approach is often difficult to guarantee. Alteration of the microbiota and an increase in intestinal permeability seem to be key in the development and progression of NAFLD. Therefore, the manipulation of microbiota seems to provide a promising therapeutic strategy. One way to do so is through faecal microbiota transplantation (FMT). Here, we summarize the key aspects of FMT, detail its current indications and highlight the most recent advances in NAFLD.Keywords
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