Synthesis and antitumour activity of new dendritic polyamines–(imide–DNA-intercalator) conjugates: potent Lck inhibitors
Authors:
- Miguel F. BrañaMBMiguel F. Braña
- Gema Domı́nguezGDGema Domı́nguez
- Beatriz SáezBSBeatriz Sáez
- Cynthia RomerdahlCRCynthia Romerdahl
- Simmon RobinsonSRSimmon Robinson
- Teresa BarlozzariTBTeresa Barlozzari
- 1 July 2002
- journal article
- Published by Elsevier in European Journal of Medicinal Chemistry
- Vol. 37 (7) , 541-551
Abstract
No abstract availableKeywords
This publication has 22 references indexed in Scilit:
- The Effect of Polyamine Homologation on the Transport and Cytotoxicity Properties of Polyamine−(DNA-Intercalator) ConjugatesThe Journal of Organic Chemistry, 2000
- Molecular Recognition of NADP(H) and ATP by Macrocyclic Polyamines Bearing Acridine GroupsHelvetica Chimica Acta, 1997
- Multiple DNA binding modes of anthracene-9-carbonyl-N1-spermineBioorganic & Medicinal Chemistry, 1995
- Polynitrile‐ and Polyamine‐Functional Poly(trimethylene imine) DendrimersAngewandte Chemie International Edition, 1993
- Targeting of cytotoxic agents by polyamines: synthesis of a chlorambucil–spermidine conjugateJournal of the Chemical Society, Chemical Communications, 1992
- Synthesis, structure and cytostatic activity of a series of N-substituted 3,4-diphenyl-1H-pyrrole-2,5-diones.Chemical and Pharmaceutical Bulletin, 1989
- Interactions of antitumor drugs with natural DNA: proton NMR study of binding mode and kineticsJournal of Medicinal Chemistry, 1984
- "Cascade"- and "Nonskid-Chain-like" Syntheses of Molecular Cavity TopologiesSynthesis, 1978
- Potential antitumor agents. 24. Dicationic analogs of the 4'-(9-acridinylamino)alkanesulfonanilidesJournal of Medicinal Chemistry, 1977
- Tumor inhibitors. XLI. Structural elucidation of tumor inhibitory sesquiterpene lactones from Eupatorium rotundifoliumThe Journal of Organic Chemistry, 1969