Vascular invasion in stage I carcinoma of the cervix

Authors:
  • ANAnthony D. Nicastri
    Anthony D. Nicastri
  • PAPoh-Choon Ambiavagar
    Poh-Choon Ambiavagar
  • MRMaria Reinis
    Maria Reinis
  • MRMarvin Rotman
    Marvin Rotman

Abstract
Vascular invasion was identified as an important prognostic variable for all lesion sizes in 138 patients with Stage I cervical carcinoma. A matched pairs analysis, controlling for lesion size and extracervical spread, showed that vascular invasion was significantly associated with poor outcome. Regression analysis also indicated that vascular invasion contributed prognostic information beyond that available from lesion size and extracervical spread. Studies of adjunctive therapy based on the prognostic variables are recommended. Cancer 53:1175‐1180, 1984.

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