Ultrasound surgery with a toric transducer allows the treatment of large volumes over short periods of time
- 5 November 2007
- journal article
- Published by AIP Publishing in Applied Physics Letters
- Vol. 91 (19) , 193901
Abstract
Thermal ablation by physical agents is widely used in clinical settings, but it generally results in a small coagulated volume. Here, we report that a technologically advanced high intensity focused ultrasound transducer can significantly enlarge the coagulated volume over short periods of time. Eight ultrasound emitters were created by sectioning a single toric piezocomposite transducer. A single thermal lesion is created when the eight emitters perform alternative and consecutive 5s ultrasound exposures. This paper presents in vivo evidence that the coagulated volume obtained from a 40s total exposure in the liver was 8.6±4.8cm3.Keywords
This publication has 19 references indexed in Scilit:
- Current role of radiofrequency ablation for the treatment of colorectal liver metastasesBritish Journal of Surgery, 2006
- Treatment of localized prostate cancer using high‐intensity focused ultrasoundBJU International, 2005
- High-intensity focused ultrasound in the treatment of solid tumoursNature Reviews Cancer, 2005
- Extracorporeal High Intensity Focused Ultrasound Ablation in the Treatment of Patients with Large Hepatocellular CarcinomaAnnals of Surgical Oncology, 2004
- Cancer treatment by ultrasound: Increasing the depth of necrosisApplied Physics Letters, 2004
- Destruction de parenchyme hépatique par ultrasons focalisésAnnales de Chirurgie, 2003
- MRI-guided gas bubble enhanced ultrasound heating inin vivorabbit thighPhysics in Medicine & Biology, 2003
- Combination of neoadjuvant chemotherapy with cryotherapy and surgical resection for the treatment of unresectable liver metastases from colorectal carcinomaCancer, 2002
- Lamb waves in piezoelectric focused radiator as a reason for discrepancy between O’Neil’s formula and experimentThe Journal of the Acoustical Society of America, 1997
- Enzyme histochemical analysis of cell viability after argon laser-induced coagulation necrosis of the skinJournal of the American Academy of Dermatology, 1991