The formation and growth of protein precipitates in a continuous stirred‐tank reactor
Authors:
- 1 July 1986
- journal article
- research article
- Published by Wiley in AIChE Journal
- Vol. 32 (7) , 1196-1204
Abstract
Product particle size distribution data are obtained for the isoelectric precipitation of protein in a continuous stirred reactor in order to evaluate the kinetics of aggregate growth in processes for protein recovery via precipitation. Data are modeled using population balances to verify the postulated mechanism and provide a basis for evaluating results for other reactor configurations. Aggregate breakage was found to be the dominant phenomenon.Keywords
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