Inhibition of tumor growth and sensitization to chemotherapy by RNA interference targeting interleukin-6 in the androgen-independent human prostate cancer PC3 model
Authors:
Open Access
- 8 January 2011
- journal article
- Published by Wiley in Cancer Science
- Vol. 102 (4) , 769-775
Abstract
No abstract availableKeywords
This publication has 39 references indexed in Scilit:
- Enhanced sensitivity to androgen withdrawal due to overexpression of interleukin-6 in androgen-dependent human prostate cancer LNCaP cellsBritish Journal of Cancer, 2009
- From pathogenesis to prevention of castration resistant prostate cancerThe Prostate, 2009
- Persistent Activation of Stat3 Signaling Induces Survivin Gene Expression and Confers Resistance to Apoptosis in Human Breast Cancer CellsClinical Cancer Research, 2006
- Androgen Receptor SignalingCancer Research, 2004
- Interleukin‐6: minor player or starring role in the development of hormone‐refractory prostate cancer?BJU International, 2003
- NF-κB in cancer: from innocent bystander to major culpritNature Reviews Cancer, 2002
- Interleukin-6 Is an Autocrine Growth Factor in Human Prostate CancerThe American Journal of Pathology, 2001
- Interleukin-6- and Cyclic AMP-Mediated Signaling Potentiates Neuroendocrine Differentiation of LNCaP Prostate Tumor CellsMolecular and Cellular Biology, 2001
- Interleukin-6 Induces G1Arrest through Induction of p27Kip1, a Cyclin-Dependent Kinase Inhibitor, and Neuron-like Morphology in LNCaP Prostate Tumor CellsBiochemical and Biophysical Research Communications, 1999
- Two Signals Are Necessary for Cell Proliferation Induced by a Cytokine Receptor gp130: Involvement of STAT3 in Anti-ApoptosisImmunity, 1996