A Prospective Study of the Development of Diabetes in Relatives of Patients with Insulin-Dependent Diabetes
Authors:
- Noel K. MaclarenNMNoel K. Maclaren
- Jeffrey KrischerJKJeffrey Krischer
- Rebecca P. SpillarRSRebecca P. Spillar
- Janet H. SilversteinJSJanet H. Silverstein
- Desmond A. SchatzDSDesmond A. Schatz
- Sherwin SchwartzSSSherwin Schwartz
- John MaloneJMJohn Malone
- Shirish ShahSSShirish Shah
- Constance VadheimCVConstance Vadheim
- Jerome I. RotterJRJerome I. Rotter
Open Access
- 25 October 1990
- journal article
- research article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 323 (17) , 1167-1172
Abstract
The presence of cytoplasmic islet-cell autoantibodies has been recognized as a risk factor for the development of diabetes mellitus in relatives of patients with insulin-dependent diabetes mellitus (IDDM), but the magnitude of the risk is unknown, as is the influence of other factors, such as age, sex, and race.Keywords
This publication has 31 references indexed in Scilit:
- Natural history of incidental hyperglycemia and glycosuria of childhoodThe Journal of Pediatrics, 1989
- TEN-YEAR FOLLOW-UP STUDY OF ISLET-CELL ANTIBODIES AND CHILDHOOD DIABETES MELLITUSThe Lancet, 1989
- Identification of insulin-dependent diabetes mellitus before the onset of clinical symptomsThe Journal of Pediatrics, 1988
- Progress toward standardization of cytoplasmic islet cell-antibody assayDiabetes, 1987
- Maturity-Onset Diabetes of Youth in Black AmericansNew England Journal of Medicine, 1987
- Impaired Insulin Action in PubertyNew England Journal of Medicine, 1986
- First-Degree Relatives of Patients with Type I Diabetes MellitusNew England Journal of Medicine, 1985
- Validity of WHO Criteria for Classification of Newly Diagnosed Diabetics* 1)Experimental and Clinical Endocrinology & Diabetes, 1985
- Islet-Cell Antibodies and Beta-Cell Function in Monozygotic Triplets and Twins Initially Discordant for Type I Diabetes MellitusNew England Journal of Medicine, 1983
- Nonparametric Estimation from Incomplete ObservationsJournal of the American Statistical Association, 1958