Isolation of a human ceruloplasmin cDNA clone that includes the N‐terminal leader sequence
Authors:
- 28 July 1986
- journal article
- Published by Wiley in FEBS Letters
- Vol. 203 (2) , 185-190
Abstract
A number of cDNA clones encoding human ceruloplasmin were identified using two mixed oligonucleotide probes. One of these clones was shown by DNA sequence analysis to span from the complete N‐terminal leader sequence to 114 amino acids short of the C‐terminus. The leader sequence consists of 19 primarily hydrophobic amino acids. Northern blot analysis of RNA from human liver showed two species of ceruloplasmin mRNA; a minor species of 3600 nucleotides and a major one of 4400 nucleotides.Keywords
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