Structural insights into the activation of GLP-1R by a small molecule agonist
- 28 July 2020
- journal article
- letter
- Published by Springer Nature in Cell Research
- Vol. 30 (12) , 1140-1142
Abstract
No abstract availableKeywords
This publication has 11 references indexed in Scilit:
- Full-length human GLP-1 receptor structure without orthosteric ligandsNature Communications, 2020
- Activation of the GLP-1 receptor by a non-peptidic agonistNature, 2020
- Phase-plate cryo-EM structure of a biased agonist-bound human GLP-1 receptor–Gs complexNature, 2018
- Crystal structure of the GLP-1 receptor bound to a peptide agonistNature, 2017
- Cryo-EM structure of the activated GLP-1 receptor in complex with a G proteinNature, 2017
- Efficacy and safety of glucagon‐like peptide‐1 receptor agonists in type 2 diabetes: A systematic review and mixed‐treatment comparison analysisDiabetes, Obesity and Metabolism, 2017
- An intrinsic agonist mechanism for activation of glucagon-like peptide-1 receptor by its extracellular domainCell Discovery, 2016
- Glucagon-Like Peptide-1 and Its Class B G Protein–Coupled Receptors: A Long March to Therapeutic SuccessesPharmacological Reviews, 2016
- The structure and function of the glucagon‐like peptide‐1 receptor and its ligandsBritish Journal of Pharmacology, 2012
- A Small Molecule Ligand of the Glucagon-like Peptide 1 Receptor Targets Its Amino-terminal Hormone Binding DomainJournal of Biological Chemistry, 2001