Cell-Mediated Cytotoxicity to Muscle in Polymyositis

Authors:
  • RDR. L. Dawkins
    R. L. Dawkins
  • FMF. L. Mastaglia
    F. L. Mastaglia
Publisher website
Google Scholar
Abstract
Immunologic injury to cultures of skeletal muscle was studied in patients with polymyositis by means of a 51Cr release method that allows quantitation of myocyte injury. Lymphocyte-mediated myotoxicity was elevated in a group of nine patients with active disease (p<0.001) but was normal in four patients with inactive disease. There was no evidence of antibody-mediated cytotoxicity.

This publication has 8 references indexed in Scilit: