Méthode générale d'obtention des α-céto esters β-fluorés

Authors:
  • AOAli Ourari
    Ali Ourari
  • RCRoger Condom
    Roger Condom
  • RGRoger Guedj
    Roger Guedj
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Abstract
A general method of synthesis of 3-alkyl (or aryl) 3-fluoro 2-oxo esters is described. The opening of glycidic esters with HF–pyridine (70% w/w), followed by oxidation with Jones reagent, give the corresponding derivatives of fluoropyruvic esters in good yields.