Choroidal Features of Acute Macular Neuroretinopathy via Optical Coherence Tomography Angiography and Correlation With Serial Multimodal Imaging

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Abstract
Acute macular neuroretinopathy (AMN), originally described by Bos and Deutman in 1975,1 is a rare, idiopathic condition characterized by acute-onset, paracentral scotoma with dark-reddish, wedge-shaped fundus lesions, with apices pointing toward the fovea.1 Characteristic spectral-domain optical coherence tomography (SD-OCT) findings have been described, including hyperreflectance of the outer retinal layers in the acute phase, particularly the outer plexiform layer (OPL) and outer nuclear layer (ONL), with thinning of these layers seen in follow-up.2-5 Acute macular neuroretinopathy is more common in young patients, predominantly women, and has been associated with numerous risk factors including oral contraceptive use, caffeine intake, preeclampsia, and viral illness.2 The condition usually improves spontaneously over weeks to months, with some patients experiencing persistent mildly decreased vision or scotomata.1-3

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