Efficient Dehydration of Aldoximes to Nitriles with TiCl3(OTf)

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Abstract
Aromatic, alicyclic, olefinic as well as heterocyclic aldoximes, were dehydrated to their corresponding nitriles with 0.15 molar equivalents of TiCl3(OTf) in sealed tube at 80°C in 85-97% yield.

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