Artificial intelligence-based algorithms for the diagnosis of retinopathy of prematurity
Authors:
Open Access
- 7 October 2025
- journal article
- review article
- Published by Wiley in Cochrane Database of Systematic Reviews
- Vol. 2025 (10) , CD016047
Abstract
Objectives This is a protocol for a Cochrane Review (diagnostic). The objectives are as follows: To assess the diagnostic performance of AI‐based algorithms in comparison to the established reference standard of clinical diagnosis labels for ROP. Secondary objectives To undertake a critical examination of potential sources of heterogeneity influencing model performance by conducting subgroup analysis by: demographics of the study population (race or ethnicity); type of input data (images only, clinical variables only, or a combination of both); the fundamental methodologies adopted by the AI algorithms (CNN or DNN); and scanner type (Retcam, Forus, or Pheonix ICON).Keywords
This publication has 53 references indexed in Scilit:
- Use of an Artificial Intelligence-Generated Vascular Severity Score Improved Plus Disease Diagnosis in Retinopathy of PrematurityOphthalmology, 2024
- Artificial Intelligence for Retinopathy of PrematurityOphthalmology, 2022
- ACCURACY OF RETINOPATHY OF PREMATURITY DIAGNOSIS BY RETINAL FELLOWSRetina, 2010
- Telemedicine for Retinopathy of Prematurity Diagnosis: Evaluation and ChallengesSurvey of Ophthalmology, 2009
- Agreement among pediatric ophthalmologists in diagnosing plus and pre-plus disease in retinopathy of prematurityJournal of American Association for Pediatric Ophthalmology and Strabismus, 2008
- Interexpert Agreement of Plus Disease Diagnosis in Retinopathy of PrematurityArchives of Ophthalmology (1950), 2007
- The International Classification of Retinopathy of Prematurity RevisitedArchives of Ophthalmology (1950), 2005
- Revised Indications for the Treatment of Retinopathy of PrematurityArchives of Ophthalmology (1950), 2003
- Incidence and Early Course of Retlnonathy of PrematurityOphthalmology, 1991
- Multicenter Trial of Cryotherapy for Retinopathy of PrematurityArchives of Ophthalmology (1950), 1988