Long-term cognitive and neurological outcome of preterm infants with postnatally acquired CMV infection through breast milk

Authors:
Publisher website
Google Scholar
Abstract
Introduction Long-term follow-up data on preterm infants with breast milk–acquired postnatal cytomegalovirus (CMV) infection are sparse. Aim To systematically evaluate the long-term cognitive outcome and prevalence of cerebral palsy (CP) in patients after postnatal CMV infection. Patients and methods All surviving infants 4 years. A blinded and controlled matched-pairs design was used with gestational age, gender and date of birth as matching criteria. Results Of 50 eligible children, 42 (84%) could be tested. There was no difference in the prevalence of cerebral palsy. Following CMV infection during their hospital stay, infants had significantly lower results in the simultaneous processing scale of the K-ABC (p=0.029) after correction for additional risk factors like socioeconomic status (SES). Results for the sequential and achievement scales were only slightly reduced (p>0.05). Conclusions It seems possible that breast milk-acquired CMV infection has a detrimental influence on cognitive development of preterm infants.

This publication has 20 references indexed in Scilit: