Choice of observational study design impacts on measurement of antipsychotic risks in the elderly: a systematic review
Open Access
- 8 June 2012
- journal article
- review article
- Published by Springer Nature in BMC Medical Research Methodology
- Vol. 12 (1) , 72
Abstract
Antipsychotics are frequently and increasingly prescribed to treat the behavioural symptoms associated with dementia despite their modest efficacy. Evidence regarding the potential adverse events of antipsychotics is limited and little is known about the longer-term safety of these medicines in the elderly. The aim of this review was to determine the impact of the choice of observational study design and methods used to control for confounding on the measurement of antipsychotic risks in elderly patients.Keywords
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