Development of di-arylated 1,2,4-triazole-based derivatives as therapeutic agents against breast cancer: synthesis and biological evaluation

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Abstract
The most potent derivative (4q, IC 50 = 4.8 μM) of the newly synthesized diarylated 1,2,4-triazole series displays several hallmarks of apoptosis in the MCF-7 breast cancer cells and favourable metabolic stability in diverse liver microsomes.
Funding Information
  • Anusandhan National Research Foundation (SCP/2022/000121)
  • Ministry of Education, India

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