Spectinomycin Resistance in Neisseria spp. Due to Mutations in 16S rRNA
Authors:
- 1 May 2000
- journal article
- research article
- Published by American Society for Microbiology in Antimicrobial Agents and Chemotherapy
- Vol. 44 (5) , 1365-1366
Abstract
Spectinomycin resistance in clinical isolates of Neisseria meningitidis and Neisseria gonorrhoeae was found to be due to mutations G1064C and C1192U ( Escherichia coli numbering) in 16S rRNA genes, respectively.Keywords
This publication has 17 references indexed in Scilit:
- High-Level Chloramphenicol Resistance inNeisseria meningitidisNew England Journal of Medicine, 1998
- A new mutation in 16S rRNA ofEscherichia coliconferring spectinomycin resistanceNucleic Acids Research, 1995
- Spectinomycin interacts specifically with the residues G1064and C1192in 16S rRNA, thereby potentially freezing this molecule into an inactive conformationNucleic Acids Research, 1994
- Constitutive heterochromatin in early embryogenesis of Drosophila melanogasterMolecular Genetics and Genomics, 1991
- Cloning and nucleotide base sequence analysis of a spectinomycin adenyltransferase AAD(9) determinant from Enterococcus faecalisAntimicrobial Agents and Chemotherapy, 1991
- A detailed model of the three-dimensional structure of Escherichia coli 16 S ribosomal RNA in situ in the 30 S subunitJournal of Molecular Biology, 1988
- Spectinomycin resistance at site 1192 in 16S ribosomal RNA of E. coli: an analysis of three mutantsBiochimie, 1987
- Effect of Spectinomycin Use on the Prevalence of Spectinomycin-Resistant and of Penicillinase-ProducingNeisseria GonorrhoeaeNew England Journal of Medicine, 1987
- Nucleotide sequence of a spectinomycin adenyltransferase AAD(9) determinant from Staphylococcus aureus and its relationship to AAD(3″) (9)Molecular Genetics and Genomics, 1985
- Antibiotic resistance mutations in 16S and 23S ribosomal RNA genes ofEscherichia coliNucleic Acids Research, 1984