Organocatalytic enantioselective Mannich and retro-Mannich reactions and combinations of these reactions to afford tetrasubstituted α-amino acid derivatives
Authors:
Open Access
- 15 December 2023
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Organic & Biomolecular Chemistry
- Vol. 22 (3) , 477-481
Abstract
Catalytic asymmetric Mannich reactions and kinetic resolutions via retro-Mannich reactions were developed. The combination of these reactions afforded tetrasubstituted α-amino acid derivatives with er >99 : 1.Keywords
Funding Information
- Okinawa Institute of Science and Technology Graduate University
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