Effect of Dietary Protein on the Response of Rainbow Trout ( Salmo gairdneri ) to Aflatoxin B 1 2 3

Authors:
  • DLD. J. Lee
    D. J. Lee
  • RSR. O. Sinnhuber
    R. O. Sinnhuber
  • JWJ. H. Wales
    J. H. Wales
  • GPG. B. Putnam
    G. B. Putnam
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Abstract
Diets containing either 49.5% or 32% casein or fish protein concentrate (FPC) were fed to young rainbow trout (Salmo gairdneri) for 12 months. Five levels [0, 2, 6, 18, and 54 parts per billion (ppb)) of aflatoxin B1 (AFB1) were given in each of four different diets. A 30-fish sample was taken at 6, 9, and 12 months to determine the influence of diet on the carcinogenicity of AFB1. Both levels of casein produced similar hepatoma incidences at each level of AFB1, The diet high in FPC produced more tumors than did the casein diets at 2, 6, and 18 ppb AFB1 whereas fish fed the diet low in FPC had a significantly (P<0.05) lower hepatoma incidence than did the other three groups. The liver size (percent body wt) was smaller at higher toxin levels in all instances. The growth of fish given 32% casein was less than that of the other groups.