Role of toll-like receptors in lung cancer
Authors:
- Wen-Sen WuWWWen-Sen Wu
- Fu ZhangFZFu Zhang
- Yi JiangYJYi Jiang
- Yue FanYFYue Fan
- Heng-Xiao FangHFHeng-Xiao Fang
- Ju LongJLJu Long
- 4 February 2014
- journal article
- review article
- Published by Taylor & Francis in Journal of Receptors and Signal Transduction
- Vol. 34 (5) , 342-344
Abstract
Lung cancer is a leading cause of death world-wide and the long-term survival rate for patients with lung cancer is one of the lowest for any cancer. Toll-like receptors (TLRs), evolutionarily conserved innate, are expressed in a wide variety of tissues and cell types, and they play key role in the innate immune system. TLRs have been found to be expressed by some kinds of tumor cells. However, what is the biological function of TLRs on tumor cells and whether human lung cancer cells can express TLRs remain to be fully understood. This review was performed to sum up the role of TLRs in lung cancer.Keywords
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