CGG Repeat-Associated Non-AUG Translation Utilizes a Cap-Dependent Scanning Mechanism of Initiation to Produce Toxic Proteins
Authors:
- 1 April 2016
- journal article
- Published by Elsevier in Molecular Cell
- Vol. 62 (2) , 314-322
Abstract
No abstract availableKeywords
Funding Information
- National Institutes of Health (F31NS090883)
- National Institutes of Health (F32NS089124)
- National Institutes of Health (K08NS069809)
- National Institutes of Health (R01NS086810)
- National Institutes of Health (T32GM007315)
- Health Services Research and Development (1I01BX001689)
- Health Services Research and Development (1I21BX001841)
- University of Michigan
This publication has 30 references indexed in Scilit:
- Ribosome Profiling of Mouse Embryonic Stem Cells Reveals the Complexity and Dynamics of Mammalian ProteomesCell, 2011
- Initiation of Translation of the FMR1 mRNA Occurs Predominantly through 5′-End-Dependent Ribosomal ScanningJournal of Molecular Biology, 2011
- Non-ATG–initiated translation directed by microsatellite expansionsProceedings of the National Academy of Sciences, 2010
- The mechanism of eukaryotic translation initiation and principles of its regulationNature Reviews Molecular Cell Biology, 2010
- Upstream open reading frames cause widespread reduction of protein expression and are polymorphic among humansProceedings of the National Academy of Sciences, 2009
- Regulation of Translation Initiation in Eukaryotes: Mechanisms and Biological TargetsCell, 2009
- Downstream control of upstream open reading frames: Figure 1.Genes & Development, 2006
- Functional characterization of IRESes by an inhibitor of the RNA helicase eIF4ANature Chemical Biology, 2006
- The (CGG)n repeat element within the 5' untranslated region of the FMR1 message provides both positive and negative cis effects on in vivo translation of a downstream reporterHuman Molecular Genetics, 2003
- Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomesCell, 1986