The Zinspy Family of Fluorescent Zinc Sensors: Syntheses and Spectroscopic Investigations
Authors:
- 1 December 2004
- journal article
- Published by American Chemical Society (ACS) in Inorganic Chemistry
- Vol. 43 (26) , 8310-8317
Abstract
Four fluorescent sensors designed for Zn(II) detection that contain a fluorescein reporting group and a pyridyl-amine-thioether derivatized ligand moiety were prepared and their photophysical properties characterized. These "Zinspy" sensors are water soluble and generally display approximately 1.4- to approximately 4.5-fold fluorescence enhancement upon Zn(II) coordination, depending upon fluorescein halogenation and the number and nature of the zinc-binding appendages. The Zinspy sensors exhibit improved selectivity for zinc compared to the di-(2-picolyl)amine-based Zinpyr family.Keywords
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