Mg0-promoted selective C–F bond cleavage of trifluoromethyl ketones: a convenient method for the synthesis of 2,2-difluoro enol silanes

Authors:
  • HAHideki Amii
    Hideki Amii
  • TKTakeshi Kobayashi
    Takeshi Kobayashi
  • YHYasushi Hatamoto
    Yasushi Hatamoto
  • KUKenji Uneyama
    Kenji Uneyama
Publisher website
Google Scholar
Abstract
2,2-Difluoro enol silyl ethers were readily prepared by Mg0 promoted selective defluorination of trifluoromethyl ketones in the presence of TMSCl, which involves C–F bond cleavage.