Immunotherapy of Cancer

Author:
  • JDJohn R. Durant
    John R. Durant

Abstract
This issue of the Journal includes reports by two different groups of investigators concerning their experience with adoptive immunotherapy for cancer.1 , 2 A total of 48 responses (8 complete, 28 partial, and 12 minor) are reported among 146 patients (of the 156 who were entered) treated with a variety of doses and schedules of interleukin-2 and lymphokine-activated killer (LAK) cells. Among 46 evaluable patients (of 49 entered) who received the highest tolerable doses of interleukin-2 alone, seven responses (one complete, five partial, and one minor) are reported.Since the first 25 patients treated with interleukin-2 and LAK cells were described in . . .