Role of Antifungal Susceptibility Testing in Non-Aspergillus Invasive Mold Infections

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Abstract
No clinical breakpoints are available to delineate antifungal drug efficacy in non-Aspergillus invasive mold infections (NAIMI). In this analysis of 39 NAIMI episodes, minimal inhibitory concentration (MIC) of the first-line antifungal drug was the most important predictor of therapeutic response. For amphotericin B, an MIC≤0.5 μg/ml was significantly associated with better 6 week outcomes.

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