Reduced dopamine transporter binding in patients with juvenile myoclonic epilepsy

Authors:
  • TWT-B Robins Wahlin
    T-B Robins Wahlin
  • AJA. Jucaite
    A. Jucaite
  • PLP. Lindstrom
    P. Lindstrom
  • CHC. Halldin
    C. Halldin
  • ISI. Savic
    I. Savic

Abstract
Background: Behavioral and cognitive problems are frequently encountered in juvenile myoclonic epilepsy (JME). The underlying mechanisms are unknown. Based on previous data showing that the dopamine system is involved in motor as well as cognitive functions, we tested whether JME may be associated with changes in this system, and if such changes are linked to interictal dysfunctions in these patients.

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