New insights into the natural course and clinical relevance of Modic changes over 2 years following lumbar limited discectomy: analysis of prospective collected data
Open Access
- 4 May 2019
- journal article
- research article
- Published by Springer Nature in European Spine Journal
- Vol. 28 (11) , 2551-2561
Abstract
Few retrospective studies have addressed Modic changes (MC) following lumbar spine surgery, though it is usually assumed that MC increase in grade and incidence. To test this conventional wisdom, we investigated the natural course of MC following primary lumbar limited discectomy with two-year follow-up. In addition, a possible clinical relevance to those changes was assessed.Keywords
This publication has 29 references indexed in Scilit:
- The location of Modic changes in the lumbar spine: a meta-analysisEuropean Spine Journal, 2016
- Pathobiology of Modic changesEuropean Spine Journal, 2016
- Possible role of autoimmune reaction in Modic Type I changesMedical Hypotheses, 2011
- What happens to Modic changes following lumbar discectomy? Analysis of a cohort of 41 patients with a 3- to 5-year follow-up periodJournal of Neurosurgery: Spine, 2010
- Chronic axial compression of the mouse tail segment induces MRI bone marrow edema changes that correlate with increased marrow vasculature and cellularityJournal of Orthopaedic Research, 2010
- Modic changes, possible causes and relation to low back painMedical Hypotheses, 2008
- Changes in Vertebral Bodies Adjacent to Acutely Narrowed Intervertebral DiscsSpine, 2007
- Modic changes following lumbar disc herniationEuropean Spine Journal, 2007
- Degenerative disk disease: assessment of changes in vertebral body marrow with MR imaging.Radiology, 1988
- MR imaging of marrow changes adjacent to end plates in degenerative lumbar disk diseaseAmerican Journal of Roentgenology, 1987