Prebiotic synthesis of the major classes of iron–sulfur clusters
Open Access
- 11 February 2025
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Chemical Science
- Vol. 16 (11) , 4614-4624
Abstract
Greater concentrations of hydrosulfide lead to the prebiotic formation of higher nuclearity Fe–S peptides, culminating in a putative nitrogenase-like [6Fe–9S] cluster. Higher nuclearity clusters are more stable with lower reduction potential.Keywords
Funding Information
- Simons Foundation (40102359, 40103183)
- Gordon and Betty Moore Foundation (11479)
- Agence Nationale de la Recherche (17-EURE-0003)
- Alfred P. Sloan Foundation (G-2022-19518)
- European Cooperation in Science and Technology (CA15133)
This publication has 90 references indexed in Scilit:
- Prebiotic Environmental Conditions Impact the Type of Iron‐Sulfur Cluster FormedChemSystemsChem, 2024
- Peptide Mimics of the Cysteine‐Rich Regions of HapX and SreA Bind a [2Fe‐2S] Cluster In VitroAdvanced Biology, 2024
- Secondary structure analysis of peptides with relevance to iron–sulfur cluster nestingJournal of Computational Chemistry, 2018
- Synthesis of an All‐Ferric Cuboidal Iron–Sulfur Cluster [FeIII4S4(SAr)4]Angewandte Chemie International Edition, 2018
- The NMR contribution to protein–protein networking in Fe–S protein maturationJBIC Journal of Biological Inorganic Chemistry, 2018
- Combining a Nitrogenase Scaffold and a Synthetic Compound into an Artificial EnzymeAngewandte Chemie International Edition, 2015
- Glutathione-coordinated [2Fe–2S] cluster is stabilized by intramolecular salt bridgesJBIC Journal of Biological Inorganic Chemistry, 2015
- Ester‐Mediated Amide Bond Formation Driven by Wet–Dry Cycles: A Possible Path to Polypeptides on the Prebiotic EarthAngewandte Chemie International Edition, 2015
- On the Evolution of Protein Folds: Are Similar Motifs in Different Protein Folds the Result of Convergence, Insertion, or Relics of an Ancient Peptide World?Journal of Structural Biology, 2001
- The Seven‐Component Reaction**Angewandte Chemie International Edition, 1993