Kidney Proximal Tubular Epithelial-Specific Overexpression of Netrin-1 Suppresses Inflammation and Albuminuria through Suppression of COX-2-Mediated PGE2 Production in Streptozotocin-Induced Diabetic Mice
Authors:
- Riyaz MohamedRiyaz Mohamed
- Calpurnia JayakumarCJCalpurnia Jayakumar
- Punithavathi V. RanganathanPRPunithavathi V. Ranganathan
- Vadivel GanapathyVGVadivel Ganapathy
- Ganesan RameshGanesan Ramesh
Open Access
- 1 December 2012
- journal article
- Published by Elsevier in The American Journal of Pathology
- Vol. 181 (6) , 1991-2002
Abstract
No abstract availableKeywords
Funding Information
- National Institutes of Health
This publication has 40 references indexed in Scilit:
- Intracellular Kinases Mediate Increased Translation and Secretion of Netrin-1 from Renal Tubular Epithelial CellsPLOS ONE, 2011
- Exome Sequencing Reveals Cubilin Mutation as a Single-Gene Cause of ProteinuriaJournal of the American Society of Nephrology, 2011
- Podocyte COX-2 Exacerbates Diabetic Nephropathy by Increasing Podocyte (Pro)renin Receptor ExpressionJournal of the American Society of Nephrology, 2011
- Risk for ESRD in Type 1 Diabetes Remains High Despite RenoprotectionJournal of the American Society of Nephrology, 2011
- Cubilin Is Essential for Albumin Reabsorption in the Renal Proximal TubuleJournal of the American Society of Nephrology, 2010
- The role of tubular injury in diabetic nephropathyEuropean Journal of Internal Medicine, 2009
- Netrin-1 Overexpression Protects Kidney from Ischemia Reperfusion Injury by Suppressing ApoptosisThe American Journal of Pathology, 2009
- Impaired Tubular Uptake Explains Albuminuria in Early Diabetic NephropathyJournal of the American Society of Nephrology, 2009
- The Role of Inflammatory Cytokines in Diabetic NephropathyJournal of the American Society of Nephrology, 2008
- Effect of TNF-α inhibition on urinary albumin excretion in experimental diabetic ratsActa Diabetologica, 2007