Enteral Nutrition Improves Clinical Outcome and Shortens Hospital Stay After Cancer Surgery

Authors:
  • LPLiya Pan
    Liya Pan
  • PZPing Zhang
    Ping Zhang
  • XLXinxin Liu
    Xinxin Liu
  • GWGuohao Wu
    Guohao Wu
  • YWYanong Wang
    Yanong Wang
  • YLYuxiu Liu
    Yuxiu Liu
  • NLNing Li
    Ning Li
  • JLJieshou Li
    Jieshou Li
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Abstract
The aim of our study was to investigate whether medium-chain triglyceride (MCT) and protein-enriched enteral nutrition (EN) could improve protein level and clinical outcomes in postoperative patients with gastrointestinal cancer. A randomized clinical trial was performed. A population of 229 patients with gastrointestinal cancer was enrolled and allocated to two groups: (a) 114 patients received MCT and protein-enriched EN (Group I) and (b) 115 patients received an isocaloric EN (Group II). The total calorie was 25 kcal/kg/day and the time period of full dose of EN must be at least five days. The three plasma proteins were improved after the EN support in both groups (p < .05). But, the increase of prealbumin in Group I was higher than that in Group II (p < .05). Episodes of diarrhea rate were equal and the postoperative infectious complications were not different between both groups. The length of hospital stay was shorter in Group I (18.4 ± 12 vs. 24.5 ± 15 d; p < .05). MCT and protein-enriched EN improves the prealbumin level and shortens the length of hospital stay in patients with gastrointestinal cancer without a high rate of adverse reaction, which may be due to high content of MCT and protein in EN.

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