The Influence of Prazosin and Propranolol on Serum Lipids and Atherosclerosis in Standard Fed Pigs
Authors:
- 13 March 2009
- journal article
- research article
- Published by Wiley in Acta Pharmacologica et Toxicologica
- Vol. 54 (4) , 270-272
Abstract
The influence of prazosin and propranolol on serum lipids and atherosclerosis was evaluated in standard fed pigs during a 9 mo. experimental period. The incidence and severity of atherosclerotic lesions was very low, and no difference could be observed neither between the 2 drugs nor between the drug groups and the placebo group. Prazosin and propranolol induced no marked change in the serum lipid profile. The results could be explained by the very low fat contnet, 3.6%, in the present standard diet.Keywords
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