Molecular Characterization of Hemophilia A Patients in Duhok, Iraq
Open Access
- 1 January 2023
- journal article
- research article
- Published by Polaris in Pharmacophore
- Vol. 14 (6) , 20-27
Abstract
The gene for coagulation factor VIII in hemophilia has more than 250 distinct mutations, and documentation of these mutations can predict the clinical phenotype, the likelihood of developing an FVIII inhibitor, and how an individual will react to the induction of immune tolerance. The current study set out to identify common mutations underlying hemophilia in a single center from Duhok/Iraq. All enrolled patients had molecular studies using inverse shifting PCR (IS-PCR) and limited sequencing toKeywords
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