KINETIC FORMULATIONS FOR ENZYMIC REACTIONS INVOLVING TWO SUBSTRATES
Authors:
- J. Tze-Fei WongJWJ. Tze-Fei Wong
- Charles S. HanesCHCharles S. Hanes
- 1 June 1962
- journal article
- research article
- Published by Canadian Science Publishing in Canadian Journal of Biochemistry and Physiology
- Vol. 40 (6) , 763-804
Abstract
The general mechanism for enzymic group-transfer reactions is shown to be of considerable complexity. In order to deal with this complexity, an analysis has been made of the structure of steady-state rate equations, which permits the establishment of direct relationships between specified features of mechanism and of rate behavior. This has opened up the possibility of a featurewise approach for the progressive elucidation of complex enzymic mechanisms. In particular, a theoretical basis has been provided for the comprehensive consideration and systematic differentiation of mechanisms of enzymic group-transfer reactions.Keywords
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