Hygromycin and epihygromycin from a bacterium, Corynebacterium equi No. 2841.

Authors:
  • YWYoshiharu Wakisaka
    Yoshiharu Wakisaka
  • KKKenzo Koizumi
    Kenzo Koizumi
  • YNYoji Nishimoto
    Yoji Nishimoto
  • MKMasaaki Kobayashi
    Masaaki Kobayashi
  • NTNaoki Tsuji
    Naoki Tsuji

Abstract
A newly isolated bacterium which produces antibacterial substances was taxonomically characterized and identified with C. equi. The major antibiotic produced was hygromycin. The minor component, newly named epihygromycin, was an epimer of hygromycin as evident by spectroscopic evidences and chemical conversions. The presence of epihygromycin the metabolites of Streptomyces noboritoensis (reported to be a hygromycin producer) was observed.

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