POLYCYCLIC AROMATIC HYDROCARBON-DNA ADDUCTS IN BELUGA WHALES FROM THE ARCTIC
Authors:
- 1 May 1997
- journal article
- research article
- Published by Taylor & Francis in Journal of Toxicology and Environmental Health
- Vol. 51 (1) , 1-4
Abstract
The Arctic is still relatively pristine in nature, but it is also vulnerable to pollution because contaminants originating from midlatitudes are transported to the Arctic by atmospheric processes, ocean currents, and rivers (Muir et al., 1992). Recognition of this fact of Arctic vulnerability has resulted in a Declaration on the Protection of the Arctic Environment by eight Arctic countries. A manifest aim of this declaration is to develop an Arctic Monitoring and Assessment Program. We report here on the presence of measurable levels of polycyclic aromatic hydrocarbon-DNA adducts, including relatively high levels in Arctic beluga (Delphinapterus leucas). These results lend support to the value of developing biological assessment programs for Arctic wildlife.Keywords
This publication has 10 references indexed in Scilit:
- Cellular and Molecular Mechanisms of Asbestos Carcinogenicity: Implications for BiopersistenceEnvironmental Health Perspectives, 1994
- Pathology and toxicology of beluga whales from the St. Lawrence Estuary, Quebec, Canada. Past, present and futureScience of The Total Environment, 1994
- Human Exposure Monitoring, Dosimetry, and Cancer Risk Assessment: The Use of Antisera Specific for Carcinogen-DNA Adducts and Carcinogen-Modified DNADrug Metabolism Reviews, 1994
- Age-dependent increases of DNA adducts (I-compounds) in human and rat brain DNAMutation Research/DNAging, 1993
- Aromatic DNA-carcinogen adducts in beluga whales from the Canadian Arctic and Gulf of St LawrenceMarine Pollution Bulletin, 1991
- SHORT COMMUNICATION: Natural environment surpasses polluted environment in inducing DNA damage in fishCarcinogenesis, 1989
- What is a Safe Level of Polycyclic Aromatic Hydrocarbons for Fish: Subchronic Toxicity Study on Winter Flounder (Pseudopleuronectes americanus)Canadian Journal of Fisheries and Aquatic Sciences, 1988
- Interlaboratory comparison of antisera and immunoassays for benzo[a] pyrene-diol-epoxide-I-modified DNACarcinogenesis, 1988
- Formation and Persistence of Benzo(a)pyrene Metabolite-DNA AdductsEnvironmental Health Perspectives, 1985
- Benzo[alpha]pyrene metabolism, activation and carcinogenesis: role and regulation of mixed-function oxidases and related enzymes.Physiological Reviews, 1980