Role of atrial natriuretic peptide and oxytocin in gastric emptying delay induced by right atrial stretch in rats
Authors:
- Raimundo C. PalhetaRPRaimundo C. Palheta
- Moisés T. B. da SilvaMSMoisés T. B. da Silva
- Ana Débora N. P. GeorgiiAGAna Débora N. P. Georgii
- Camila M. S. SilvaCSCamila M. S. Silva
- Rômmulo C. L. SiqueiraRSRômmulo C. L. Siqueira
- Wagner L. ReisWRWagner L. Reis
- Silvia G. RuginskSRSilvia G. Ruginsk
- Lucila L. K. EliasLELucila L. K. Elias
- José Antunes-RodriguesJAJosé Antunes-Rodrigues
- Armênio A. SantosASArmênio A. Santos
- 1 March 2025
- journal article
- Published by American Physiological Society in American Journal of Physiology-Regulatory, Integrative and Comparative Physiology
- Vol. 328 (3) , R396-R407
Abstract
We suggest a cardiogastric reflex with the participation of neuroendocrine mediators, which contributes to regulating liquid balance in the animal’s body. Atrial natriuretic peptide and oxytocin are substances recognized for participating in diuresis and regulating the transit of liquids in the gastrointestinal tract in situations of cardiac volume overload, as was simulated with atrial stretching in the present experimental model.Keywords
Funding Information
- Fundação de Amparo à Ciência e Tecnologia do Estado de Pernambuco (APQ/1303-4.01/12)
- Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (Finance Code 001)
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