A novel oridonin analogue, CYD0682, suppresses breast cancer growth, angiogenesis, and metastasis by inhibiting the ANGPTL4/MAPK signaling axis
Authors:
Open Access
- 1 September 2025
- journal article
- Published by KEAI Publishing in Genes & Diseases
- Vol. 12 (5) , 101681
Abstract
No abstract availableFunding Information
- Guangdong Pharmaceutical University (2024ZZ10)
- Basic and Applied Basic Research Foundation of Guangdong Province (2023A1515010459)
- University of Texas Medical Branch
- Administration of Traditional Chinese Medicine of Jilin Province (20242048, 20251209)
- Innovative Research Group Project of the National Natural Science Foundation of China
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- DNA methylation mediated down-regulation of ANGPTL4 promotes colorectal cancer metastasis by activating the ERK pathwayJournal of Cancer, 2021
- Regio- and Stereospecific Synthesis of Oridonin D-Ring Aziridinated Analogues for the Treatment of Triple-Negative Breast Cancer via Mediated Irreversible Covalent WarheadsJournal of Medicinal Chemistry, 2018
- Enhanced effects of novel oridonin analog CYD0682 for hepatic fibrosisJournal of Surgical Research, 2015